Polynucleotides are increasingly being mentioned as a treatment for skin improvement. But what exactly do they do and what can you expect from them? Unlike fillers, polynucleotides do not focus on volume, but on repairing and strengthening the skin itself. In this blog, we explain how it works, who it is suitable for and whether it actually gives results.

Skin repair and renewal

What exactly are polynucleotides?

Polynucleotides are small building blocks of DNA that play an important role in skin repair and renewal. In cosmetic treatments, these substances are used to support the skin from within, rather than adding or filling something. Whereas fillers primarily provide volume, polynucleotides focus on skin quality . They help the skin repair itself better, improve hydration and support collagen production. As a result, the skin feels firmer and looks more even and healthy.

Treatments with polynucleotides, such as PolyPhil, are often chosen by people who want to improve their skin in a subtle and natural way. The result is not an immediate change in shape, but a gradual improvement in skin texture and appearance.

Activating the skin

How do polynucleotides work in the skin?

Polynucleotides are applied by small injections into the skin, where they stimulate the natural repair process. Rather than adding anything, they activate the skin to improve itself.

Among other things, they support:

  • Cell repair, allowing the skin to better renew itself
  • Hydration, as the skin retains more moisture
  • Collagen production, which increases firmness and elasticity
  • Restoration of the skin barrier, making the skin more resilient

This process takes time. The skin gradually becomes stronger and healthier, so the results build up in the weeks following treatment. The effect is subtle, but noticeable in the structure and appearance of the skin.

Additional skin support

For whom are polynucleotides suitable?

Polynucleotides is especially suitable for people who want to improve their skin quality without drastic changes. It is not a treatment for volume or contour, but for skin that could use some extra support.

You can think of:

  • Dull or tired-looking skin
  • Fine lines you want to soften
  • Dark circles or thin skin around the eyes
  • Skin that feels less firm
  • Skin damaged by sun, stress or aging

The treatment is often chosen by people who want a natural improvement, without it being visible that something has been done. It is also a good option if you don’t want fillers (yet), but notice that your skin is losing some quality. During a consultation we always check if this treatment suits your skin and expectations. Sometimes a combination with other treatments is more effective.

Polynucleotides

Treatments at Aepril Clinics

At Aepril Clinics, we work with polynucleotides based on PolyPhil Salmon DNA. This treatment is tailored to the area you want to improve, as the skin around eyes, face and hair structure each require a different approach.

Depending on your needs, you can choose from:

During a consultation, we look at which variant best suits your skin and goals. This way we ensure a treatment that suits what your skin needs.

Do polynucleotides really work?

Yes, polynucleotides can improve the skin, but do not expect an immediate visible effect as with fillers. The treatment works gradually and focuses on skin quality. Think better hydration, smoother skin and increased firmness.

Results build up in the weeks following treatment and are best seen after several sessions. It is especially suitable if you opt for a subtle, natural improvement.

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Skin improvement comparison

How is it different from other skin-enhancing treatments?

Within skin improvement, there are several treatments, each of which works in a different way. The difference is mainly in the purpose and depth at which they work.

  • Polynucleotides focus on repair and skin quality. They support the skin’s natural process and improve structure and hydration.
  • Profhilo focuses mainly on intensive hydration and gives the skin a fresh, healthy glow.
  • Belotero Revive Combines hydration with a slight improvement in skin texture.
  • Radiesse Hyperdiluted and Sculptra stimulate the production of collagen and provide increased firmness over time.

Unsure if polynucleotides suit you?

Polynucleotides can be a great step if you want to improve your skin naturally. But not every treatment suits every skin. That’s why at Aepril Clinics we take the time to work with you to see what is the best choice for you. During a consultation, we discuss your needs, assess your skin and give honest advice. Sometimes polynucleotides are the right approach, sometimes another treatment is more appropriate.

Want to know what suits your skin? You are welcome in our clinic in Utrecht or Hengelo.

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